Health Care
Pharmaceuticals
Healthcare Delivery Systems
Salvona Health Care has a broad array of patented nanotechnology engineered solutions for the pharmaceutical market addressing challenges ranging from lifecycle extension of proven drugs to delivering promising new drugs emerging at the cutting edge of the biotechnology industry. The company has developed a broad range of proprietary nanotechnology platforms, including nanospheres, microspheres, invisible patches, and biodegradable devices, to bridge the current technology gaps in controlled drug delivery.
Nanotechnology engineered drug delivery systems and devices are expected to capture significant applications in the health care market as they have different or improved performance characteristics on existing delivery systems. Due to their small size, these systems and devices can permeate through cell walls and easily move across many biological barriers, such as gut epithelium or leaky endothelium in tumor tissues. As we control and manipulate the surface characteristics of these systems, the prospect of both passive and active targeting can also be greatly improved. All Salvona's technology platforms consist of food approved or GRAS (generally regarded as safe) materials following FDA regulations and manufactured through environmentally friendly processes, thus easy to commercialize.
Controlled drug delivery is a widely recognized high-growth sector within the US $300 billion pharmaceutical market (PR Newswire, New York August 2001). Many of the highly profitable pharmaceutical drug patents are expected to expire over the next decade, resulting in an estimated loss of $30-$40 billion in annual product revenues as generic drugs enter the market. This change is accelerating the industry’s constant need to “build the pipeline” of new compounds, and to rapidly enter new markets. Naturally, these trends are creating new challenges and opportunities in drug discovery and are a driving force in the drug delivery market. Drug delivery technologies are patentable and so new products can be developed giving old drugs surrogate protection at a relatively low cost. This is immensely attractive for the pharmaceutical industry as billions of dollars in drugs are coming off patent protection, seeing as they want to keep the generics industry away from their hard earned profits.
The nanotechnology platforms developed in Salvona target the following market segments:
1. Oral Hygiene – two nano and submicron technology platforms to address the needs of the oral hygiene market and OTC drug treatment for the oral cavity. Three patents in this field have been granted with one product on the market and several others in the pipeline. The one product is currently being used to protect flavors and other actives from peroxide.
2. Oral Drug Delivery- oral delivery and targeted delivery of poorly soluble drugs
3. Oral Vaccination and Protein Delivery
4. Topical and Transdermal Drug Delivery – nanotechnology engineered soluble patches for topical and transdermal drug delivery.
5. Diagnostic – A biodegradable timer that degrades inside the body in the gastrointestinal track over time in a controlled manner. This high-end diagnostic device (wireless endoscopy) is taken orally and dissolves in a predetermined time.
6. Implantable and Biodegradable Devices – Biodegradable matrices that are marketed as temporarily implants for tissue regeneration and for diagnostic products.
7. Gene Therapy – Delivery of DNA, RNA, and proteins through nanotechnology.
8. Targeted Delivery for Cancer Therapy – Delivery of actives to solid tumors through nanotechnology
9. Inhaled Drug Delivery – Pulmonary drug delivery of nanospheres through spray or aerosol applications.
Salvona has a successful track record in commercializing cost-effective controlled-release technologies for oral hygiene, diagnostic, and personal care products.
Salvona's vision is to create market-changing nanotechnology engineered delivery systems and biodegradable devices based on understanding the business opportunities in the Health Care market. The company’s goal is to play a leading role in the controlled drug delivery market and capitalize on business opportunities that exist at the intersection of nanotechnology and traditional pharmaceuticals.
Our business model is to license the rights for our proprietary nanotechnology platforms for prescription drugs and to commercialize non-regulated OTC drug products comprising these technologies. The licensing will be for a specific drug to a specific company, thus allowing us to license the same technology to multiple prospects. The combined licensing and product commercialization avenues will enable us to maximize the value of our nanotechnology platforms.