Why Controlled Release?
What do Controlled Release Systems have to offer?
Controlled Release Systems are used to modify the way functional and active ingredients are being delivered. These controlled release systems are encapsulation technologies that are used to formulate innovative and highly functional products with unique features. Some of the major benefits of controlled release delivery systems are as follows:
1. Long Lasting Release
Sustain the release of active ingredients in use so that the active is released for a longer duration of time. The technology provides better utilization of active ingredients over time.1. Long Lasting Release
This graph shows concentration change as a function of time from the time of application. Notice how actives normally experience a short burst in concentration followed by a rapid decline, whereas actives released from a controlled release delivery system experience a prolonged concentration at the effective level (threshold). This graph aims to demonstrate passive control systems, where release kinetics from the system cannot be changed once applied. Theses systems are not triggered, but rather designed to enable a prolonged delivery of critical actives.
Why do we need this? Because keeping the active at an effective level ensures product efficacy and provides benefits to the consumer.
2. Triggered Release
Release of active ingredients on demand, triggered by environmental factors or the consumer's action, is a more intelligent form of controlled release systems.
The graph above demonstrates active delivery systems that are dormant, however upon triggering, the release is activated. The dormant effect (no release) is beneficial to enhance stability of non-stable actives in the the formulation, until the product is triggered by the environment or by the consumer. The active ingredients remain encapsulated and protected. This beneficial tool can be used in many products, such as deodorants, in which body moisture (sweat) can trigger the release of a pleasant smell once the consumer begins to sweat. In this case, the moisture triggers the delivery system to release a malodor countering fragrance.
3. Targeted Delivery/ Vector
Release the active materials at the desired location for localized and targeted release.
This graph demonstrates how controlled release systems can assist in targeting the active to reach a specific place. The system is beneficial for products that require their applications reaching a certain area to perform better, such as a drug attaching to cancer cells for cancer therapy; a conditioner depositing actives onto hair before a customer rinses it off; or even anti-aging applications, where the active must reach deep within the skin dermis before truly becoming effective.
What are the traditional types of Controlled Release Systems?
Encapsulation
- Homogeneous dispersion of the active in a solid phase. The active diffuses out of the matrix over time.
- Active entrapped and coated by a polymer system. The properties of the material coating the active are controlling the release rate.
What are Nanotechnology Delivery Systems?
Delivery systems at the near-atomic, or less than 1,000 nanometers typically 0.1nm to 100nm constitute nanotechnology. Particles with diameter of 100-1000nm are considered sub-micron systems.
Salvona Awarded for Nano Technology
Nanotech Briefs announced Salvona as a winner of the second annual Nano 50 Awards, which recognize the top 50 technologies, products, and innovators that have significantly impacted - or are expected to impact - the state of the art in nanotechnology. The winners of the Nano 50 awards are the "best of the best" - the innovative people and designs that will move nanotechnology to key mainstream markets.
Nano 50 nominations were judged by a panel of nanotechnology experts. The technologies, products, and innovators receiving the 50 highest scores were named Nano 50 award winners. View the Nano50 Here
Nanotech Briefs announced Salvona as a winner of the second annual Nano 50 Awards, which recognize the top 50 technologies, products, and innovators that have significantly impacted - or are expected to impact - the state of the art in nanotechnology. The winners of the Nano 50 awards are the "best of the best" - the innovative people and designs that will move nanotechnology to key mainstream markets.
Nano 50 nominations were judged by a panel of nanotechnology experts. The technologies, products, and innovators receiving the 50 highest scores were named Nano 50 award winners. View the Nano50 Here
Send Page To a Friend
All content copyright Salvona Technologies™ 2007
Phone: (609) 655-0173 Fax: (609) 655-9291 Email: Info@Salvona.com
Administration