HydroSal® Natural Antiseptics

PID# 8419-02

Provides long-lasting protection from microbes using alcohol-free, natural plant extracts with proven antiseptic and antifungal properties.

  • Provides long-lasting protection through surface adhesion.
  • Water-triggered burst provides extra protection where it is needed most, on wet surfaces.
  • Easy to formulate, water-compatible system contains an optimized blend of ingredients for broad spectrum inhibition at low dosage.


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Natural Antiseptics are safe for your skin and the environment. HydroSal® technology provides long-lasting protection from microbes, using alcohol-free, natural plant extracts with proven antiseptic and antifungal properties without causing lasting damage to your skin or the planet.

Some natural antiseptics include witch hazel, thyme, calendula, tea tree oil, eucalyptus, lavender and grapefruit seed extract. The botanical extracts have natural antiseptic properties and can be used to treat or stave off infected blemishes, pimples and acne. Possessing natural antimicrobial, antibacterial and anti-fungal actions, such extracts, are effective for many skin conditions.

However, natural extracts should be used with care because they can irritate the skin and are only effective when used in an optimal concentration.

HydroSal® NAS incorporates a complex of plant extracts at an optimized level into a single delivery system. HydroSal® uses gentle plant products with a dosing technology for the skin and other surfaces. The technology works well as an antiseptic treatment. It also encourages tissue and skin healing and doesn’t cause the skin to break down.

HydroSal® technology

HydroSal® is composed of a core with a shell coating. The system’s core provides a reservoir for the natural antiseptic ingredients. The ingredients diffuse slowly from the core through the shell. HydroSal® NAS is diluted and suspended in water for a spray, gel or other form of finished product. When the product is applied to a surface, the solvent evaporates and the technology will create a disinfected area.

Extended Efficacy on Surfaces

The Efficiency of HydroSal® NAS was determined in a high-traffic public restroom, comparing HydroSal® NAS and NAS Free, each put on a floor tile. After 48 hours of normal use, the areas were swabbed). After swabbing, the NAS Free and HydroSal NAS areas were wiped for 10 seconds with a paper towel dampened with water, then swabbed again after 5 minutes.

The results are presented in this photo. Areas treated with HydroSal NAS showed a reduced number of bacteria compared to the control. Wetting the surface further reduced the number of bacteria. We relate the reduction of the bacteria to the ability of the HydroSal® to release more of the NAS ingredients when the surface is exposed to water.

Cultures collected from bathroom surfaces tested at t=48 hours of normal use, one area with NAS Free and another with HydroSal NAS. The top row is before wetting, and the bottom row is after.

Improves Retention on Skin

The retention of HydroSal® NAS on skin was determined with volunteers using a lotion containing HydroSal NAS. The product was applied to the arms of volunteers and remained for a period of 6 hours. The skin was extracted with alcohol to determine the level of HydroSal NAS that remained on the skin.

Comparison of HydroSal NAS retained on skin of volunteers treated with spray at equivalent concentration of HydroSal NAS from either HydroSal NAS vs. NAS Free. Analyzed via HPLC.

Efficacy of the NAS Blend

HS NAS (μl/ml)
S. aureus
E. coli
S. typhimurium
K. pneumoniae
M. smegmatis
C. albicans
A. niger

Minimum Inhibitory Concentration (MIC) of the blend required to use for different bacteria. A dosage of 40 ul/ml would be sufficient to inhibit microorganisms.

Technical Data

Appearance @ 20°C
Opaque liquid
Skin care products such as creams and lotions
White to off-white
pH (1 % solution)
6.5 ± 1.0
Loading 5
Shelf Life (months) 18
Usage Level (wt%) 2.5-10%
Storage (°C)
Closed container at 12-32°


(W/W %)
HydroSal® Natural Antiseptic
Salvona Pre-Mix S #5016
DI Water